Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.41 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803455 | 0.92 | MAPT (0.44) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6664644 | 0.90 | AVPR2 (0.44) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6669291 | 0.90 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6665119 | 0.88 | EIF2AK3 (0.44) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6667516 | 0.87 | TP53 (0.42) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6667512 | 0.87 | EIF2AK3 (0.43) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6671845 | 0.86 | CYP11B1 (0.43) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6667068 | 0.86 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6808866 | 0.85 | SLC12A2 (0.46) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6664878 | 0.85 | EIF2AK3 (0.48) | MAPTNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |