Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 8/20 | 0.40 |
| ▸ | HTR2C | P28335 | 8/20 | 0.40 |
| ▸ | HTR2B | P41595 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669113 | 0.90 | LMNA (0.41) | TP53LMNAMAPTHTR2AHTR2C | |
| SCHEMBL6667216 | 0.89 | RIPK1 (0.44) | TP53LMNAMAPTHTR2AHTR2C | |
| SCHEMBL6670249 | 0.87 | MAPT (0.42) | TP53LMNAMAPTNPC1RAB9A | |
| SCHEMBL6804642 | 0.84 | MTTP (0.47) | TP53LMNAMAPTALDH1A1 | |
| SCHEMBL6664419 | 0.84 | HTR2A (0.41) | TP53LMNAMAPTHTR2AHTR2C | |
| SCHEMBL6802265 | 0.84 | RIPK1 (0.42) | TP53LMNAMAPTNPC1RAB9A | |
| SCHEMBL6664644 | 0.83 | AVPR2 (0.44) | TP53LMNAMAPTNPC1RAB9A | |
| SCHEMBL6803455 | 0.83 | MAPT (0.44) | TP53LMNAMAPTNPC1RAB9A | |
| SCHEMBL6806284 | 0.83 | RIPK1 (0.43) | TP53LMNAMAPTNPC1RAB9A | |
| SCHEMBL6666805 | 0.82 | CASP3 (0.43) | TP53LMNAMAPTHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |