Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363229 | 0.78 | MEN1 (0.64) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL14909268 | 0.77 | NPC1 (0.51) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5865023 | 0.77 | LTA4H (0.56) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL31528260 | 0.76 | RAB9A (0.46) | KMT2AALDH1A1MAPTLMNARAB9A | |
| SCHEMBL1101199 | 0.74 | NPC1 (0.77) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL29360828 | 0.74 | NPC1 (0.77) | MEN1KMT2AALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL4754679 | 0.73 | NPC1 (0.74) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL31528273 | 0.73 | LIPE (0.53) | KMT2AALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7646409 | 0.72 | FFAR4 (0.51) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL7113088 | 0.72 | FFAR4 (0.51) | ALDH1A1MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432695-A1 | A PROCESS FOR THE STEREOSELECTIVE SYNTHESIS OF 2-HYDROXYMETHYL-CHROMANS | Wyeth (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003031429-A1 | A PROCESS FOR THE STEREOSELECTIVE SYNTHESIS OF 2-HYDROXYMETHYL-CHROMANS | WYETH (US) | 2003-04-17 | — | — | WO | disclosed |