12-Aminododecanoic Acid

12-Aminododecanoic Acid

SCHEMBL6670903

NCCCCCCCCCCCC(=O)O.O=C1CCCCCN1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.52
THRB P10828 2/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
PLG P00747 1/20 0.52
ALOX15 P16050 1/20 0.52
SLC6A2 P23975 1/20 0.52
RECQL P46063 1/20 0.52
SLC6A3 Q01959 1/20 0.52
NFKB1 P19838 2/20 0.48
CYP2D6 P10635 1/20 0.48
FKBP5 Q13451 1/20 0.48
CRBN Q96SW2 1/20 0.48
BLM P54132 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
TSHR P16473 2/20 0.41
OR51E2 Q9H255 1/20 0.41
GABRR3 A8MPY1 1/20 0.41
GABRP O00591 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL7787311 1.00 LMNA (0.52) LMNATHRBKMT2AMEN1ALDH1A1
Aminocaproic Acid SCHEMBL7776910 1.00 LMNA (0.52) LMNATHRBKMT2AMEN1ALDH1A1
Adipic Acid SCHEMBL2887286 1.00 LMNA (0.52) LMNATHRBKMT2AMEN1ALDH1A1
Adipic Acid SCHEMBL262118 1.00 LMNA (0.52) LMNATHRBKMT2AMEN1ALDH1A1
Aminocaproic Acid SCHEMBL11214069 1.00 LMNA (0.52) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL261431 1.00 LMNA (0.52) LMNATHRBKMT2AMEN1ALDH1A1
12-Aminododecanoic Acid SCHEMBL27428500 1.00 LMNA (0.52) LMNATHRBKMT2AMEN1ALDH1A1
5-Aminovaleric Acid SCHEMBL28827887 0.98 NFKB1 (0.50) LMNATHRBKMT2AMEN1ALDH1A1
Octanoic Acid SCHEMBL8989223 0.93 GPR84 (0.45) LMNATHRBKMT2AMEN1ALDH1A1
SCHEMBL6764194 0.92 FKBP5 (0.57) LMNAKMT2AMEN1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240012-B1 HIGH TEMPERATURE RELEASE FILMS HONEYWELL INT INC (US) 2004-09-22 EP disclosed
EP-1240012-A2 HIGH TEMPERATURE RELEASE FILMS Honeywell International Inc. (US) 2002-09-18 EP disclosed
US-6270909-B1 USED IN PREPARING ARTICLES COMPRISING CURED FIBER REINFORCED EPOXY, PHENOLIC OR POLYACRYLATE WHICH ARE USED AS AEROSPACE STRUCTURAL ELEMENTS HONEYWELL INTERNATIONAL INC. 2001-08-07 US disclosed
WO-2000059720-A2 HIGH TEMPERATURE RELEASE FILMS HONEYWELL INTERNATIONAL INC. AND MITSUI CHEMICALS, INC. (US) 2000-10-12 WO disclosed