Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267655 | 0.85 | SIRT1 (0.35) | SIRT1MCL1BCHEACHEPTPN1 | |
| SCHEMBL5265253 | 0.85 | SIRT1 (0.35) | SIRT1MCL1BCHEACHEPTPN1 | |
| SCHEMBL5370812 | 0.85 | PTPN1 (0.32) | SIRT1MCL1PTPN1ALOX5PTGES | |
| SCHEMBL3669027 | 0.84 | BCHE (0.36) | SIRT1MCL1BCHEACHEPTPN1 | |
| SCHEMBL3670779 | 0.84 | BCHE (0.36) | SIRT1MCL1BCHEACHEPTPN1 | |
| SCHEMBL15442718 | 0.84 | BCHE (0.36) | SIRT1MCL1BCHEACHEPTPN1 | |
| SCHEMBL6690567 | 0.75 | BCHE (0.38) | SIRT1MCL1BCHEACHEPTGES | |
| SCHEMBL5371313 | 0.72 | GAA (0.33) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5620552 | 0.69 | SIRT1 (0.41) | SIRT1MCL1BCHEACHEMAOB | |
| SCHEMBL5523109 | 0.69 | SIRT1 (0.41) | SIRT1MCL1BCHEACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169304-B1 | 8-8, 6-6 AND 6-8 CATECHIN AND EPICATECHIN DIMERS AND METHODS FOR THEIR PREPARATION | MARS INC (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6156912-A | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation | MARS, INCORPORATED (US) | 2000-12-05 | — | — | US | disclosed |