Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523109 | 1.00 | SIRT1 (0.41) | SIRT1BCHEACHEMCL1PIN1 | |
| SCHEMBL18427307 | 0.92 | PIN1 (0.38) | BCHEACHEPIN1MAOBMAPT | |
| SCHEMBL5268318 | 0.92 | PIN1 (0.38) | BCHEACHEPIN1MAOBMAPT | |
| SCHEMBL5265501 | 0.92 | PIN1 (0.38) | BCHEACHEPIN1MAOBMAPT | |
| SCHEMBL4620243 | 0.88 | SIRT1 (0.38) | SIRT1BCHEACHEMCL1PIN1 | |
| SCHEMBL5620180 | 0.86 | MEN1 (0.42) | SIRT1BCHEACHEMCL1MAOB | |
| SCHEMBL5698022 | 0.86 | MEN1 (0.42) | SIRT1BCHEACHEMCL1MAOB | |
| SCHEMBL6690567 | 0.86 | BCHE (0.38) | SIRT1BCHEACHEMCL1PIN1 | |
| SCHEMBL3669027 | 0.83 | BCHE (0.36) | SIRT1BCHEACHEMCL1PIN1 | |
| SCHEMBL3670779 | 0.83 | BCHE (0.36) | SIRT1BCHEACHEMCL1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282598-B2 | Synthetic methods for preparing procyanidin oligomers | MARS, INC. | 2007-10-16 | — | — | US | disclosed |
| EP-1175415-B1 | SYNTHETIC METHODS FOR PREPARING PROCYANIDIN DIMERS | MARS INC (US) | 2006-10-18 | — | — | EP | disclosed |
| EP-1686123-A2 | Synthetic methods for preparing procyanidin oligomers | Mars, Incorporated (US) | 2006-08-02 | — | — | EP | disclosed |
| US-7015338-B1 | Synthetic methods for preparing procyanidin oligomers | MARS INCORPORATED (US) | 2006-03-21 | — | — | US | disclosed |
| US-6864377-B2 | Synthetic methods for preparing procyanidin oligomers | MARS INCORPORATED (US) | 2005-03-08 | — | — | US | disclosed |
| US-20040176441-A1 | Synthetic methods for preparing procyanidin oligomers | MARS INCORPORATED | 2004-09-09 | — | — | US | disclosed |
| US-20030114691-A1 | Synthetic methods for preparing procyanidin oligomers | MARS INCORPORATED | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176441-A1 | Synthetic methods for preparing procyanidin oligomers | C9, NOD2, CASP8 | SIRT1 697/4885BCHE 650/4885ACHE 2230/4885 |
| US-20030114691-A1 | Synthetic methods for preparing procyanidin oligomers | C9, NOD2, CASP8 | SIRT1 697/4885BCHE 650/4885ACHE 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.