Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 3/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CREB1 | P16220 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371313 | 0.87 | GAA (0.33) | LMNAHPGDTHRATHRB | |
| SCHEMBL5267655 | 0.87 | SIRT1 (0.35) | PTPN1ALOX5PTGESSIRT1MCL1 | |
| SCHEMBL5265253 | 0.87 | SIRT1 (0.35) | PTPN1ALOX5PTGESSIRT1MCL1 | |
| SCHEMBL6671393 | 0.85 | SIRT1 (0.34) | PTPN1ALOX5PTGESSIRT1MCL1 | |
| SCHEMBL3670779 | 0.76 | BCHE (0.36) | PTPN1ALOX5SIRT1MCL1 | |
| SCHEMBL3669027 | 0.76 | BCHE (0.36) | PTPN1ALOX5SIRT1MCL1 | |
| SCHEMBL6690567 | 0.67 | BCHE (0.38) | PTGESSIRT1LMNAMCL1 | |
| SCHEMBL7410422 | 0.66 | DYRK1A (0.41) | — | |
| SCHEMBL7413524 | 0.63 | KDM4E (0.41) | HPGD | |
| SCHEMBL6670685 | 0.63 | CYP3A4 (0.41) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268240-B2 | Synthetic methods for polyphenols | MARS, INC. | 2007-09-11 | — | — | US | disclosed |
| US-6849746-B2 | Synthetic methods for polyphenols | MARS, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040235941-A1 | Dimer digallate compositions | MARS, INCORPORATED | 2004-11-25 | — | — | US | disclosed |
| US-20040236123-A1 | Synthetic methods for polyphenols | M&M/MARS INC. | 2004-11-25 | — | — | US | disclosed |
| EP-1169304-B1 | 8-8, 6-6 AND 6-8 CATECHIN AND EPICATECHIN DIMERS AND METHODS FOR THEIR PREPARATION | MARS INC (US) | 2004-09-29 | — | — | EP | disclosed |
| US-20030176620-A1 | Synthetic methods for polyphenols | MARS INCORPORATED | 2003-09-18 | — | — | US | disclosed |
| US-6528664-B2 | Synthetic methods for polyphenols | MARS, INCORPORATED | 2003-03-04 | — | — | US | disclosed |
| EP-1027345-B1 | SYNTHETIC METHODS FOR POLYPHENOLS | MARS INC (US) | 2003-02-19 | — | — | EP | disclosed |
| US-20020128493-A1 | Coupling flavonoid-like compounds having protected hydroxy groups by functionalizing the C-4; oxidative dehydrogenation to form dimers and oligomers; efficiency; anticarciogenic agents; breast cancer | MARS, INCORPORATED | 2002-09-12 | — | — | US | disclosed |
| US-6420572-B1 | FLAVANOID DERIVATIVES AND PHENOLIC DERIVATIVES WITH HALOGENATION | MARS, INCORPORATED | 2002-07-16 | — | — | US | disclosed |
| US-6156912-A | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation | MARS, INCORPORATED (US) | 2000-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236123-A1 | Synthetic methods for polyphenols | MLN, NQO1, NOD2 | PTPN1 2464/4885ALOX5 749/4885PTGES 263/4885 |
| US-20020128493-A1 | Coupling flavonoid-like compounds having protected hydroxy groups by functionalizing the C-4; oxidative dehydrogenation to form dimers and oligomers; efficiency; anticarciogenic agents; breast cancer | GPX4, NOX4, TPD52L2 | PTPN1 3514/4885ALOX5 522/4885PTGES 927/4885 |
| US-20040235941-A1 | Dimer digallate compositions | NOD2, GID4, GPX4 | PTPN1 2999/4885ALOX5 954/4885PTGES 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.