Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | DUT | P33316 | 2/20 | 0.39 |
| ▸ | TK1 | P04183 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739758 | 0.87 | KIF11 (0.41) | KIF11DUTCYP2C19CYP2C9ALOX15 | |
| SCHEMBL9693942 | 0.84 | CYP2C9 (0.45) | KIF11DUTTK1CYP2C19CYP2C9 | |
| SCHEMBL23037535 | 0.84 | CYP2C9 (0.45) | KIF11DUTTK1CYP2C19CYP2C9 | |
| SCHEMBL15892819 | 0.80 | KIF11 (0.39) | KIF11DUTTK1CYP2C19CYP2C9 | |
| SCHEMBL841606 | 0.79 | DUT (0.48) | KIF11DUTTK1CYP2C19CYP2C9 | |
| SCHEMBL465454 | 0.78 | TK1 (0.46) | KIF11DUTTK1CYP2C19CYP2C9 | |
| SCHEMBL6522822 | 0.78 | TK1 (0.46) | KIF11DUTTK1CYP2C19CYP2C9 | |
| SCHEMBL18609340 | 0.77 | PLA2G2A (0.49) | KIF11PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL2178034 | 0.76 | KIF11 (0.44) | KIF11DUTTK1CYP2C19ALOX15 | |
| SCHEMBL4525211 | 0.76 | KIF11 (0.44) | KIF11DUTTK1CYP2C19ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775149-B1 | NOVEL PROTECTING GROUPS AND USE THEREOF IN AN IMPROVED PROCESS FOR OLIGONUCLEOTIDE SYNTHESIS | UNIV COLORADO (US) | 2004-09-22 | — | — | EP | disclosed |
| US-6008400-A | MIXING TRIMETHYLORTHOFORMATE AND AN ALCOHOL IN A SOLVENT TO PRODUCE A REACTION MIXTURE AND REMOVING THE SOLVENT TO YIELD ORTHOESTER REAGENT | REGENTS OF THE UNIVERSITY OF COLORADO, THE | 1999-12-28 | — | — | US | disclosed |
| US-5889136-A | PHOSPHORAMIDITE OLIGONUCLEOTIDE BIOSYNTHESIS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 1999-03-30 | — | — | US | disclosed |