Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRG | P23470 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HAT1 | O14929 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671405 | 0.93 | HSP90AA1 (0.40) | HSP90AA1MEN1KMT2ANR1H4NPC1 | |
| SCHEMBL7483549 | 0.83 | HSP90AA1 (0.44) | HSP90AA1MEN1KMT2ANR1H4NPC1 | |
| SCHEMBL6672645 | 0.82 | HSP90AA1 (0.42) | HSP90AA1MEN1KMT2ANR1H4NPC1 | |
| SCHEMBL6667497 | 0.81 | HSP90AA1 (0.41) | HSP90AA1MEN1KMT2ANR1H4NPC1 | |
| SCHEMBL7475445 | 0.81 | HSP90AA1 (0.44) | HSP90AA1MEN1KMT2ANR1H4NPC1 | |
| SCHEMBL6668965 | 0.80 | NR1H4 (0.39) | HSP90AA1NR1H4NPC1RAB9AALDH1A1 | |
| SCHEMBL7014028 | 0.78 | ALDH1A1 (0.37) | HSP90AA1NR1H4NPC1RAB9AALDH1A1 | |
| SCHEMBL7015592 | 0.76 | HSP90AA1 (0.40) | HSP90AA1MEN1KMT2ANR1H4NPC1 | |
| SCHEMBL7843694 | 0.75 | GAA (0.46) | ALDH1A1HTTGAA | |
| SCHEMBL6667774 | 0.74 | CHEK1 (0.46) | HSP90AA1NR1H4NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |