Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514575 | 0.92 | PKM (0.43) | KDM4CPKMSLC6A3KDM4EMAPK1 | |
| SCHEMBL4779862 | 0.83 | PKM (0.42) | KDM4CPKMSLC6A3KDM4EMAPK1 | |
| SCHEMBL907879 | 0.83 | KDM4E (0.44) | KDM4CPKMSLC6A3KDM4EMAPK1 | |
| SCHEMBL5818912 | 0.76 | SMN1; SMN2 (0.41) | KDM4CPKMSLC6A3KDM4EMAPK1 | |
| Citric Acid SCHEMBL4779312 | 0.76 | ALDH1A1 (0.40) | PKMKDM4E | |
| SCHEMBL9079443 | 0.74 | KDM4C (0.42) | KDM4CPKMSLC6A3KDM4EMAPK1 | |
| SCHEMBL4888615 | 0.74 | MAPK1 (0.41) | KDM4CPKMSLC6A3KDM4EMAPK1 | |
| SCHEMBL30223118 | 0.74 | KDM4C (0.47) | KDM4CPKMKDM4EMAPK1NPSR1 | |
| SCHEMBL7186166 | 0.73 | TBXAS1 (0.45) | — | |
| Malonic Acid SCHEMBL6672043 | 0.72 | NPSR1 (0.46) | KDM4CPKMSLC6A3KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069118-B1 | PROCESS FOR PRODUCING 4-THIAZOLYLMETHYL DERIVATIVE | SHIONOGI & CO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6506903-B1 | By reacting 4-methylthiazole with N-halosuccinimide in solvent in presence of 2,2-azobisisobutyronitrile; halogenation, catalysis | SHIONOGI & CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| EP-1069118-A1 | PROCESS FOR PRODUCING 4-THIAZOLYLMETHYL DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |