SCHEMBL6672249

SCHEMBL6672249

CN(C)S(=O)(=O)NC(=O)c1cc(-c2c(C(F)(F)F)n(C)c(=O)[nH]c2=O)ccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 18/20 0.41
SCN5A Q14524 1/20 0.40
AURKA O14965 1/20 0.38
TPX2 Q9ULW0 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6672028 0.89 SCN9A (0.33) SCN9ASCN5A
SCHEMBL9359135 0.82 GRIK1 (0.50)
SCHEMBL2413504 0.77 SCN9A (0.37) SCN9A
SCHEMBL9764699 0.71 GRIK1 (0.32)
SCHEMBL16793130 0.71 POLB (0.37) SCN9A
SCHEMBL6049362 0.69 SCN9A (0.42) SCN9ASCN5ASMN1; SMN2
SCHEMBL6217982 0.66 LMNA (0.31)
SCHEMBL6219513 0.66 GRIK1 (0.33)
SCHEMBL6545351 0.66 THRA (0.32)
SCHEMBL6670192 0.66 SCN9A (0.33) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458237-A1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2004-09-22 EP disclosed
WO-2003051122-A1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2003-06-26 WO disclosed