Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359135 | 0.79 | GRIK1 (0.50) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6672249 | 0.71 | SCN9A (0.41) | — | |
| SCHEMBL5174653 | 0.71 | GSK3A (0.36) | — | |
| SCHEMBL6545351 | 0.67 | THRA (0.32) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6219513 | 0.63 | GRIK1 (0.33) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6217982 | 0.61 | LMNA (0.31) | — | |
| SCHEMBL9354701 | 0.59 | HPGD (0.35) | — | |
| SCHEMBL8908156 | 0.59 | BCAT2 (0.43) | — | |
| SCHEMBL8301246 | 0.59 | PTGS1 (0.41) | — | |
| SCHEMBL27897618 | 0.58 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436680-A1 | HETEROCYCLIC COMPOUNDS. | CIBA GEIGY AG (CH) | 1991-07-17 | — | — | EP | disclosed |