SCHEMBL6672322

SCHEMBL6672322

CC1=C([Si](C)(C)C2c3ccccc3-c3ccccc32)CC=C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6915757 0.80 ALDH1A1 (0.30) ALDH1A1
SCHEMBL6677712 0.74 GPR3 (0.32) GPR3
SCHEMBL6675603 0.72 GPR3 (0.32) GPR3
SCHEMBL5175203 0.70 GPR3 (0.37) GPR3
SCHEMBL9632059 0.67 GPR3 (0.40) GPR3GAAALDH1A1
SCHEMBL10319624 0.67 ESR1 (0.44)
SCHEMBL5175634 0.66 GPR3 (0.46) GPR3ALDH1A1
SCHEMBL6671925 0.66 GPR3 (0.46) GPR3ALDH1A1
SCHEMBL30390148 0.66 GPR3 (0.46) GPR3ALDH1A1
SCHEMBL7053332 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 US disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed