SCHEMBL6672819

SCHEMBL6672819

N#C/C=C(\C#N)C1C(=O)C(=O)c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.37
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
CYP1A2 P05177 1/20 0.31
MAPK1 P28482 1/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 2/20 0.31
HBB P68871 2/20 0.31
ALOX15 P16050 1/20 0.31
EPHX2 P34913 1/20 0.31
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2955164 0.73 GLS (0.38) PIM1EDNRBEDNRA
SCHEMBL2955162 0.73 GLS (0.38) PIM1EDNRBEDNRA
SCHEMBL10930218 0.71 EDNRA (0.56) EDNRBEDNRAHDAC3HDAC4HDAC7
SCHEMBL6672820 0.70 PIM1 (0.38) PIM1EDNRBEDNRACYP1A2MAPK1
SCHEMBL6689616 0.69 GUSB (0.32)
SCHEMBL8629991 0.68
SCHEMBL29144668 0.67 PIM1 (0.61) PIM1EDNRBEDNRANCOR2CYP1A2
SCHEMBL28485980 0.66 HBB (0.66) EDNRBEDNRAHDAC3HDAC4HDAC7
SCHEMBL11663620 0.64 EDNRB (0.47) EDNRBEDNRANCOR2CYP1A2MAPK1
SCHEMBL29013976 0.64 HDAC3 (0.39) HDAC3HDAC4HDAC7HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985968-B1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK CO (US) 2004-10-06 EP disclosed
US-6527977-B2 Solvent dispersion EASTMAN KODAK COMPANY 2003-03-04 US disclosed
US-6455210-B1 SUPPORT, PHOTOTHERMOGRAPHIC IMAGE- RECEIVING LAYERS, AND ANTIHALATION LAYER OR FILTER LAYERS OF A DYE AND A HEXAARYLBIIMIDAZOLE IN A DISPERSION OF A HYDROPHILIC POLYMER EASTMAN KODAK COMPANY 2002-09-24 US disclosed
US-20020106590-A1 AQUEOUS THERMALLY BEACHABLE COMPOSITION USEFUL IN A PHOTOTHERMOGRAPHIC ELEMENT CARESTREAM HEALTH, INC. 2002-08-08 US disclosed
EP-1217431-A2 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2002-06-26 EP disclosed
US-6355386-B1 FOR PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY 2002-03-12 US disclosed
US-20020009656-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY 2002-01-24 US disclosed
US-6214499-B1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY 2001-04-10 US disclosed
US-6180295-B1 CONTAINING MEROCYANINE DYE EASTMAN KODAK COMPANY 2001-01-30 US disclosed
EP-0985970-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY (US) 2000-03-15 EP disclosed
EP-0985968-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY (US) 2000-03-15 EP disclosed