SCHEMBL6689616

SCHEMBL6689616

N#CC=C(C#N)C1C(=Cc2ccccc2)C(C(C#N)=CC#N)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GUSB P08236 1/20 0.32
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8629991 0.68
SCHEMBL6689621 0.68 TRPA1 (0.35) GUSBMCL1
Styrene SCHEMBL16194120 0.61 ALDH1A1 (0.58) MCL1
SCHEMBL2955164 0.61 GLS (0.38)
SCHEMBL28724754 0.59 MAPT (0.45) MCL1
Styrene SCHEMBL27464772 0.59 ALDH1A1 (0.54) MCL1
SCHEMBL3836329 0.59 MCL1 (0.53) MCL1
SCHEMBL18994292 0.58 GUSB (0.45) GUSB
SCHEMBL5409190 0.58 MAPT (0.48)
SCHEMBL28444563 0.57 ESR1 (0.44) MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004041840-A2 PEPTIDE-BOUND CHROMOGENS USED FOR DETERMINING ENZYMATIC ACTIVITIES C-CIT AG (CH) 2004-05-21 WO disclosed