SCHEMBL667286

SCHEMBL667286

O=c1ccn(C(F)(F)F)c(=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.48
DDB1 Q16531 1/20 0.44
PKM P14618 1/20 0.36
HCAR1 Q9BXC0 4/20 0.35
DUT P33316 6/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20610936 0.83 CRBN (0.45) CRBNDDB1PKMDUTALDH1A1
SCHEMBL13188311 0.80 CRBN (0.50) CRBNDDB1PKMDUTL3MBTL1
SCHEMBL10047085 0.78 CRBN (0.54) CRBNDDB1PKMDUT
SCHEMBL1722581 0.72 CRBN (0.52) CRBNDDB1DUTALDH1A1
SCHEMBL22260061 0.72 CRBN (0.47) CRBNDDB1PKMHCAR1DUT
SCHEMBL22779414 0.72 CRBN (0.47) CRBNDDB1PKMHCAR1DUT
SCHEMBL24512475 0.70 CRBN (0.44) CRBNDDB1PKMDUTALDH1A1
SCHEMBL21524576 0.70 CRBN (0.44) CRBNDDB1PKMHCAR1DUT
SCHEMBL6666896 0.70 CRBN (0.44) CRBNDDB1DUTALDH1A1LMNA
SCHEMBL21803323 0.69 PKM (0.47) CRBNDDB1PKMDUTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 943 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117660383-A Application of N-deoxyribotransferase in catalytic production of trifluridine and preparation method thereof 杭州中美华东制药有限公司 2024-03-08 CN claimed
EP-3599857-A1 HERBICIDAL MIXTURES Bayer Aktiengesellschaft (DE) 2020-02-05 EP claimed
WO-2018172442-A1 HERBICIDAL MIXTURES BAYER AKTIENGESELLSCHAFT (DE) 2018-09-27 WO claimed
CN-106892873-A A kind of preparation method of 5 trifluoromethyl uracil 内蒙古佳瑞米精细化工有限公司 2017-06-27 CN claimed
WO-2013020985-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING SPECIFIC TETRAMIC ACID DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-02-14 WO claimed
CN-1344259-A Process for the preparation of 1, 3-oxazin-6-ones and uracils and intermediates BASF AG (DE) 2002-04-10 CN claimed
WO-1994017089-A2 METHOD FOR LOCALISING AND MEASURING THE PROLIFERATION OF CANCER AND COMPOSITIONS FOR SAME THE UNIVERSITY OF LIVERPOOL (GB) 1994-08-04 WO claimed
EP-0351853-B1 Method of manufacturing trifluorothymidine YUKI GOSEI YAKUHIN KOGYO KK (JP) 1994-04-13 EP claimed
EP-0351853-A2 Method of manufacturing trifluorothymidine YUKI GOSEI KOGYO CO., LTD. (JP) 1990-01-24 EP claimed
JP-2031686-A None JP disclosed
JP-11246590-A None JP disclosed
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 US disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 US disclosed
EP-0260428-A2 Cationic surfactants and pharmaceutical compositions containing them MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-03-23 EP disclosed
EP-0258672-A2 Cationic surfactants and pharmaceutical compositions containing them MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-03-09 EP disclosed
EP-0257400-A2 Pharmaceutical compositions containing cationic surfactants MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-03-02 EP disclosed
US-3981715-A 2,3,5-Substituted-6-trifluoromethyl-1,3-diazin-4-ones herbicides AMERICAN CYANAMID COMPANY (US) 1976-09-21 US disclosed
US-3954760-A Process for producing N1 -(α-butyrolactone- and N1 (α- GILLER SOLOMON ARONOVICH 1976-05-04 US disclosed
JP-H00231686-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD CRBN 1816/4885DDB1 408/4885PKM 1615/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 CRBN 3187/4885DDB1 3515/4885PKM 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.