Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669025 | 0.75 | PTGS2 (0.76) | PTGS1PTGS2ALOX5 | |
| SCHEMBL6672311 | 0.70 | PTGS1 (0.53) | PTGS1PTGS2ALOX5 | |
| SCHEMBL6642062 | 0.70 | PTGS1 (0.53) | PTGS1PTGS2ALOX5 | |
| SCHEMBL6984374 | 0.70 | PTGS2 (0.53) | PTGS1PTGS2ALOX5 | |
| SCHEMBL8759810 | 0.69 | PTGS2 (1.00) | PTGS1PTGS2ALOX5 | |
| SCHEMBL6668333 | 0.69 | PTGS1 (0.52) | PTGS1PTGS2ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL6955055 | 0.68 | HTR1D (0.42) | PTGS1PTGS2 | |
| SCHEMBL8759670 | 0.68 | PTGS2 (0.86) | PTGS1PTGS2ALOX5 | |
| SCHEMBL13145695 | 0.66 | KDR (0.59) | ALDH1A1POLB | |
| SCHEMBL8089277 | 0.66 | PTGS1 (0.58) | PTGS1PTGS2MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879231-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-0879231-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-11-25 | — | — | EP | disclosed |
| US-5684041-A | FOR TREATING ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-04 | — | — | US | disclosed |
| WO-1997028143-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-07 | — | — | WO | disclosed |