Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670350 | 0.81 | KMT2A (0.53) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL14133155 | 0.76 | ALDH1A1 (0.64) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL6673765 | 0.74 | ALDH1A1 (0.51) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL11157838 | 0.73 | ALDH1A1 (0.67) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL6678055 | 0.72 | ALDH1A1 (0.54) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL6673810 | 0.72 | MEN1 (0.56) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL6674164 | 0.71 | ALDH1A1 (0.48) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL6677498 | 0.70 | KDM4E (0.49) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL6672876 | 0.69 | KDM5B (0.60) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL11960241 | 0.68 | ALDH1A1 (0.55) | KMT2AMEN1MAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037248-A2 | MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY | CAREX SA (FR) | 2004-05-06 | — | — | WO | disclosed |