SCHEMBL6673971

SCHEMBL6673971

COc1cccc(-c2nc(-c3ccccc3Cl)[nH]c2-c2cccc(OC)c2OC)c1OC.COc1cccc(-c2nc(-c3ccccc3Cl)[nH]c2-c2cccc(OC)c2OC)c1OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 4/20 0.48
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47
RUNX1 Q01196 1/20 0.47
CBFB Q13951 1/20 0.47
PIM1 P11309 1/20 0.47
CSNK2A2 P19784 1/20 0.47
CSNK2B P67870 1/20 0.47
PIM3 Q86V86 1/20 0.47
PIM2 Q9P1W9 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TEK Q02763 1/20 0.47
MGAM O43451 1/20 0.45
GAA P10253 1/20 0.45
SI P14410 1/20 0.45
MGAM2 Q2M2H8 1/20 0.45
TP53 P04637 2/20 0.45
MAPT P10636 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194043 0.87 TEK (0.50) AMY1AKDM4EALDH1A1HPGDPIM1
SCHEMBL29375392 0.87 TEK (0.50) AMY1AKDM4EALDH1A1HPGDPIM1
SCHEMBL10600871 0.77 MAPK14 (0.59) KDM4EALDH1A1HPGDTEKMGAM
SCHEMBL5076359 0.77 TEK (0.57) KDM4EALDH1A1HPGDRUNX1CBFB
SCHEMBL21877426 0.77 P2RX7 (0.51) KDM4EALDH1A1MGAMGAASI
SCHEMBL29581646 0.76 TEK (0.59) KDM4EALDH1A1HPGDRUNX1CBFB
SCHEMBL9496039 0.76 TEK (0.59) KDM4EALDH1A1HPGDRUNX1CBFB
SCHEMBL29895756 0.76 TEK (0.59) KDM4EALDH1A1HPGDRUNX1CBFB
SCHEMBL25772952 0.75 PDE5A (0.55) AMY1AKDM4EALDH1A1HPGDMEN1
SCHEMBL28004199 0.74 TEK (0.64) KDM4EALDH1A1HPGDRUNX1CBFB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1468332-A1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE Kodak Polychrome Graphics Company Ltd. (US) 2004-10-20 EP disclosed
EP-1453675-A1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE Kodak Polychrome Graphics Company Ltd. (US) 2004-09-08 EP disclosed
WO-2003062924-A1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2003-07-31 WO disclosed
WO-2003051631-A1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2003-06-26 WO disclosed