Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294540 | 0.93 | GPR119 (0.33) | GPR119CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL6294522 | 0.91 | GPR119 (0.32) | GPR119CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6293275 | 0.77 | — | — | |
| SCHEMBL6865770 | 0.68 | HTR6 (0.39) | — | |
| SCHEMBL4631245 | 0.68 | HTR6 (0.39) | — | |
| SCHEMBL4667157 | 0.68 | METAP1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL8022324 | 0.67 | CCR6 (0.32) | — | |
| SCHEMBL3146259 | 0.67 | CA1 (0.45) | — | |
| SCHEMBL6865388 | 0.67 | CA1 (0.45) | — | |
| SCHEMBL5199761 | 0.66 | METAP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246791-B1 | AMINOMETHYL-PHENYL-CYCLOHEXANONE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-10-27 | — | — | EP | disclosed |