Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.53 |
| ▸ | CA1 | P00915 | 7/20 | 0.53 |
| ▸ | CA2 | P00918 | 7/20 | 0.53 |
| ▸ | CA9 | Q16790 | 7/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13852882 | 0.83 | POLB (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL13852881 | 0.82 | CA1 (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6673841 | 0.80 | CA12 (0.57) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4602639 | 0.74 | KMT2A (0.55) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8972515 | 0.74 | KCNH3 (0.71) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14374438 | 0.74 | POLB (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL304437 | 0.73 | POLB (0.63) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3131322 | 0.72 | KDM4E (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL12445529 | 0.72 | KCNH3 (0.63) | CA12CA1CA2CA9CA14 | |
| SCHEMBL10516787 | 0.72 | KMT2A (0.51) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100203650-A1 | BIOMOLECULE BINDING LIGANDS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-08-12 | — | — | US | disclosed |
| US-20100203650-A1 | BIOMOLECULE BINDING LIGANDS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-08-12 | — | — | US | disclosed |
| WO-2004035199-A1 | AFFINITY ADSORBENTS FOR IMMUNOGLOBULINS | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100203650-A1 | BIOMOLECULE BINDING LIGANDS | C3AR1, GRB7, C1R | CA12 2315/4885CA1 2803/4885CA2 4376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.