Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | TXN | P10599 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 4/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13852882 | 0.97 | POLB (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14374438 | 0.89 | POLB (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL17630275 | 0.85 | AURKA (0.54) | POLBAURKAAURKBMAPK8MAPK10 | |
| SCHEMBL4094573 | 0.84 | NFKB1 (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8911586 | 0.83 | NPC1 (0.66) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4938552 | 0.83 | NFKB1 (0.55) | CA12CA1CA2CA9CA14 | |
| SCHEMBL11837292 | 0.81 | NFKB1 (0.78) | CA12CA1CA2CA9CA14 | |
| SCHEMBL21925306 | 0.81 | AURKA (0.52) | MAPTMEN1KMT2AAURKAAURKB | |
| SCHEMBL304437 | 0.81 | POLB (0.63) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6674873 | 0.80 | CA12 (0.53) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035199-A1 | AFFINITY ADSORBENTS FOR IMMUNOGLOBULINS | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |