Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26622064 | 0.84 | MTNR1A (0.54) | MTNR1AMTNR1BTAAR1 | |
| SCHEMBL27002039 | 0.84 | MTNR1A (0.66) | MTNR1AMTNR1BTAAR1 | |
| SCHEMBL7246127 | 0.82 | NQO2 (0.48) | MTNR1AMTNR1B | |
| SCHEMBL11290858 | 0.81 | TAAR1 (0.41) | TAAR1ALDH1A1HPGD | |
| SCHEMBL16428954 | 0.81 | SMN1; SMN2 (0.44) | MTNR1AMTNR1BTAAR1 | |
| SCHEMBL11376820 | 0.80 | ALDH1A1 (0.50) | TAAR1ALDH1A1HPGD | |
| SCHEMBL8550870 | 0.79 | ADRA1A (0.45) | MTNR1AMTNR1BTAAR1ALDH1A1 | |
| SCHEMBL11896371 | 0.78 | MTNR1A (0.77) | MTNR1AMTNR1BTAAR1ALDH1A1HPGD | |
| SCHEMBL443057 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL1531286 | 0.78 | ALDH1A1 (0.54) | MTNR1AMTNR1BALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |