Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653544 | 0.74 | MAPK14 (0.53) | KMT2AMEN1MAPK13MAPK12MAPK11 | |
| SCHEMBL29878293 | 0.65 | CYP3A4 (0.45) | TSHRMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5493729 | 0.65 | ALDH1A1 (0.52) | KMT2AMEN1TSHRALDH1A1KDM4E | |
| SCHEMBL10361182 | 0.64 | MMP2 (0.46) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL6538841 | 0.64 | TDP1 (0.45) | KMT2AMEN1ALDH1A1KDM4EHDAC3 | |
| SCHEMBL7196493 | 0.64 | MAPK14 (0.69) | KMT2AMEN1MAPK13MAPK12MAPK11 | |
| SCHEMBL6654067 | 0.63 | MAPT (0.47) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL11574044 | 0.63 | HPGD (0.47) | KMT2AMEN1TSHRALDH1A1HPGD | |
| SCHEMBL8002568 | 0.63 | MEN1 (0.47) | KMT2AMEN1TSHRALDH1A1POLB | |
| SCHEMBL28689599 | 0.62 | CYP3A4 (0.61) | KMT2AMEN1TSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966424-B1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMA AS (DK) | 2004-06-23 | — | — | EP | claimed |