Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092675 | 0.94 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2GPR119ALDH1A1LMNA | |
| SCHEMBL9892884 | 0.83 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL28975843 | 0.82 | GPR119 (0.55) | L3MBTL1SMN1; SMN2GPR119ALDH1A1LMNA | |
| SCHEMBL30291360 | 0.82 | GPR119 (0.55) | L3MBTL1SMN1; SMN2GPR119ALDH1A1LMNA | |
| SCHEMBL8333355 | 0.77 | L3MBTL1 (0.77) | L3MBTL1SMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL25938113 | 0.77 | L3MBTL1 (0.77) | L3MBTL1SMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL30557537 | 0.77 | L3MBTL1 (0.77) | L3MBTL1SMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL25570307 | 0.76 | NR1H2 (0.41) | L3MBTL1SMN1; SMN2GPR119ALDH1A1LMNA | |
| SCHEMBL25339309 | 0.76 | KDM4E (0.49) | GPR119LMNAUSP30NPC1MEN1 | |
| SCHEMBL20595777 | 0.76 | KDM4E (0.49) | GPR119LMNAUSP30NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041795-A1 | NOVEL INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS INC. (US) | 2004-05-21 | — | — | WO | disclosed |