SCHEMBL8092675

SCHEMBL8092675

CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)c1nc2ccccc2s1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
USP30 Q70CQ3 5/20 0.48
KDM4E B2RXH2 2/20 0.47
LMNA P02545 2/20 0.46
ALDH1A1 P00352 1/20 0.46
NPC1 O15118 1/20 0.45
GPR119 Q8TDV5 2/20 0.45
POLB P06746 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
UCHL1 P09936 2/20 0.45
NPSR1 Q6W5P4 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
CASP1 P29466 1/20 0.44
SCN4A P35499 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6675477 0.94 L3MBTL1 (0.47) L3MBTL1USP30KDM4ELMNAALDH1A1
SCHEMBL30557537 0.83 L3MBTL1 (0.77) L3MBTL1USP30KDM4ELMNAALDH1A1
SCHEMBL25938113 0.83 L3MBTL1 (0.77) L3MBTL1USP30KDM4ELMNAALDH1A1
SCHEMBL8333355 0.83 L3MBTL1 (0.77) L3MBTL1USP30KDM4ELMNAALDH1A1
SCHEMBL8079479 0.82 PREP (0.55) L3MBTL1KDM4ELMNAALDH1A1KMT2A
SCHEMBL25938123 0.82 USP30 (0.65) L3MBTL1USP30KDM4ELMNAALDH1A1
SCHEMBL25938122 0.82 USP30 (0.65) L3MBTL1USP30KDM4ELMNAALDH1A1
SCHEMBL30291360 0.81 GPR119 (0.55) L3MBTL1USP30LMNAALDH1A1GPR119
SCHEMBL28975843 0.81 GPR119 (0.55) L3MBTL1USP30LMNAALDH1A1GPR119
SCHEMBL8263228 0.80 ACE (0.55) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100273835-A1 NOVEL COMPOUNDS PROBIODRUG AG (DE) 2010-10-28 US disclosed
US-20100273835-A1 NOVEL COMPOUNDS PROBIODRUG AG (DE) 2010-10-28 US disclosed
WO-2009007415-A2 NOVEL COMPOUNDS PROBIODRUG AG (DE) 2009-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100273835-A1 NOVEL COMPOUNDS IL6, PREP, PEPD L3MBTL1 4063/4885USP30 1008/4885KDM4E 1354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.