SCHEMBL5136628

SCHEMBL5136628

CCCCN(C(=O)C(F)(F)F)[SiH](C)C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 9/20 0.41
CES1 P23141 7/20 0.39
CES2 O00748 5/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA9 Q16790 2/20 0.36
EPHX1 P07099 1/20 0.36
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP8 P22894 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4439111 0.94 FAAH (0.44) FAAHCES1CES2MEN1CYP1A2
SCHEMBL6675892 0.79 CHRM2 (0.35) FAAHCES1CES2MEN1CYP1A2
SCHEMBL5586241 0.77 FAAH (0.45) FAAHCES1CES2MEN1CYP1A2
SCHEMBL6057133 0.77 CA12 (0.50) FAAHCES1CES2MEN1CYP1A2
SCHEMBL16508865 0.75 FAAH (0.43) FAAHCES1CES2MEN1CYP1A2
SCHEMBL5620718 0.71 CHRM2 (0.30)
SCHEMBL27464446 0.71 FAAH (0.39) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2354299 0.69 MLYCD (0.39) CA12CA1CA9
SCHEMBL15216070 0.69 FAAH (0.47) FAAHCES1CES2MEN1CYP1A2
SCHEMBL29411335 0.69 FAAH (0.50) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1979019-A2 BIOACTIVE MATERIAL DELIVERY SYSTEMS COMPRISING SOL-GEL COMPOSITIONS Medlogics Device Corporation (US) 2008-10-15 EP claimed
WO-2007092043-A2 BIOACTIVE MATERIAL DELIVERY SYSTEMS COMPRISING SOL-GEL COMPOSITIONS MEDLOGICS DEVICE CORPORATION (US) 2007-08-16 WO claimed
CN-102015995-B Carbon dioxide fixing engineering microorganism for producing carbon-based target product JOULE UNLIMITED, INC. (US) 2014-10-22 CN disclosed
CN-103725717-A Method of producing Microbiological ethyl alcohol JOULE UNLTD TECHNOLOGIES INC 2014-04-16 CN disclosed
WO-2014055638-A1 RAPID ANALYSIS OF STEROIDS AND STEROID DERIVATIVES WATERS TECHNOLOGIES CORPORATION (US) 2014-04-10 WO disclosed
CN-102216463-B Microbial ethanol production JOULE BIOTECHNOLOGIES INC 2013-10-16 CN disclosed
CN-102216463-A Microbial ethanol production JOULE BIOTECHNOLOGIES INC 2011-10-12 CN disclosed
CN-1954067-B Recombinant enzyme for changing feed-back sensitivity METABOLIC EXPLORER SA 2011-08-03 CN disclosed
CN-102015995-A Carbon dioxide fixing engineering microorganism for producing carbon-based target product JOULE UNLTD INC 2011-04-13 CN disclosed
CN-1954067-A Recombinant enzyme for changing feed-back sensitivity METABOLIC EXPLORER SA (FR) 2007-04-25 CN disclosed
WO-1998059242-A1 HOMOCYSTEINE ASSAY NEXSTAR PHARMACEUTICALS, INC. (US) 1998-12-30 WO disclosed
EP-0269352-A2 Assay for sulfhydryl amino acids and methods for detecting and distinguishing cobalamin and folic acid deficiency UNIVERSITY PATENTS, INC. (US) 1988-06-01 EP disclosed