Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.36 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140677 | 0.82 | KMT2A (0.53) | KMT2APOLBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL4727586 | 0.80 | MAPT (0.59) | KMT2APOLBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL122644 | 0.80 | MAPT (0.59) | KMT2APOLBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL122645 | 0.80 | MAPT (0.59) | KMT2APOLBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL5058848 | 0.80 | L3MBTL1 (0.61) | KMT2APOLBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL5020127 | 0.79 | L3MBTL1 (0.50) | KMT2APOLBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL1217960 | 0.76 | NOD1 (0.55) | KMT2APOLBL3MBTL1NOD1CAD | |
| SCHEMBL1217963 | 0.76 | NOD1 (0.55) | KMT2APOLBL3MBTL1NOD1CAD | |
| SCHEMBL29543223 | 0.76 | L3MBTL1 (0.47) | KMT2APOLBL3MBTL1ACACBMAPT | |
| SCHEMBL5020129 | 0.75 | L3MBTL1 (0.44) | KMT2APOLBL3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037159-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM | OBETHERAPY BIOTECHNOLOGY (FR) | 2004-05-06 | — | — | WO | disclosed |