Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CAD | P27708 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122644 | 1.00 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL122645 | 1.00 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL929076 | 0.93 | KDM4E (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Pyruvate SCHEMBL6571338 | 0.93 | MAPT (0.56) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Pyruvate SCHEMBL6573546 | 0.93 | MAPT (0.56) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL930333 | 0.93 | KDM4E (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Cysteamine SCHEMBL20768365 | 0.91 | ALOX15 (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL9292612 | 0.86 | KDM4E (0.44) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL9292614 | 0.86 | KDM4E (0.44) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL4990411 | 0.86 | CAD (0.44) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231886-A4 | TOPICAL SKIN COMPOSITION | ACCESS BUSINESS GROUP INT LLC (US) | 2005-10-12 | — | — | EP | claimed |
| CN-1424900-A | Topical skin composition | TONDAR COMMERCIAL GROUP INTERN (US) | 2003-06-18 | — | — | CN | claimed |
| US-20030095959-A1 | Topical skin composition | ACCESS BUSINESS GROUP INTERNATIONAL LLC. | 2003-05-22 | — | — | US | claimed |
| EP-1231886-A1 | TOPICAL SKIN COMPOSITION | Alticor Inc. (US) | 2002-08-21 | — | — | EP | claimed |
| WO-2001037788-A1 | TOPICAL SKIN COMPOSITION | ALTICOR INC. (US) | 2001-05-31 | — | — | WO | claimed |
| CN-102406607-B | Tiopronin liposome injection | HAINAN LINGKANG PHARMACEUTICAL | 2012-11-21 | — | — | CN | disclosed |
| CN-102406607-A | Tiopronin liposome injection | HAINAN LINGKANG PHARMACEUTICAL | 2012-04-11 | — | — | CN | disclosed |
| CN-101522266-A | Topical skin compositions, their preparation, and their use | ACCESS BUSINESS GROUP INT LLC (US) | 2009-09-02 | — | — | CN | disclosed |
| US-20080124409-A1 | Topical Skin Compositions, Their Preparation, and Their Use | ACCESS BUSINESS GROUP INTERNATIONAL LLC | 2008-05-29 | — | — | US | disclosed |
| US-20080081034-A1 | Topical Skin Compositions, Their Preparation, and Their Use | ACCESS BUSINESS GROUP INTERNATIONAL LLC | 2008-04-03 | — | — | US | disclosed |
| US-20080081082-A1 | Topical Skin Compositions, Their Preparation, and Their Use | ACCESS BUSINES GROUP INTERNATIONAL LLC | 2008-04-03 | — | — | US | disclosed |
| WO-2008016842-A1 | TOPICAL SKIN COMPOSITIONS, THEIR PREPARATION, AND THEIR USE | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016838-A1 | TOPICAL SKIN COMPOSITIONS, THEIR PREPARATION AND THEIR USE | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20070003536-A1 | Topical skin compositions, their preparation, and their use | ACCESS BUSINESS GROUP INTERNATIONAL LLC | 2007-01-04 | — | — | US | disclosed |
| EP-1231886-A4 | TOPICAL SKIN COMPOSITION | ACCESS BUSINESS GROUP INT LLC (US) | 2005-10-12 | — | — | EP | disclosed |
| CN-1424900-A | Topical skin composition | TONDAR COMMERCIAL GROUP INTERN (US) | 2003-06-18 | — | — | CN | disclosed |
| US-20030095959-A1 | Topical skin composition | ACCESS BUSINESS GROUP INTERNATIONAL LLC. | 2003-05-22 | — | — | US | disclosed |
| EP-1231886-A1 | TOPICAL SKIN COMPOSITION | Alticor Inc. (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001037788-A1 | TOPICAL SKIN COMPOSITION | ALTICOR INC. (US) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081034-A1 | Topical Skin Compositions, Their Preparation, and Their Use | COL14A1, MMP8, MMP1 | MAPT 1892/4885KDM4E 3279/4885THRB 4735/4885 |
| US-20080124409-A1 | Topical Skin Compositions, Their Preparation, and Their Use | COL14A1, MMP8, MMP1 | MAPT 1892/4885KDM4E 3279/4885THRB 4735/4885 |
| US-20030095959-A1 | Topical skin composition | CUTA, S100A4, KRT18 | MAPT 1787/4885KDM4E 4634/4885THRB 3415/4885 |
| US-20070003536-A1 | Topical skin compositions, their preparation, and their use | COL14A1, MMP8, MMP1 | MAPT 1892/4885KDM4E 3279/4885THRB 4735/4885 |
| US-20080081082-A1 | Topical Skin Compositions, Their Preparation, and Their Use | COL14A1, MMP8, MMP1 | MAPT 1892/4885KDM4E 3279/4885THRB 4735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.