Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645214 | 0.82 | KDM4E (0.40) | ALDH1A1TSHRHTTNPC1RAB9A | |
| SCHEMBL16726626 | 0.74 | CA12 (0.52) | ALDH1A1TSHRLMNAHTTNPC1 | |
| SCHEMBL29738634 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNAHTTNPC1 | |
| SCHEMBL6651429 | 0.71 | SOD1 (0.34) | — | |
| SCHEMBL424976 | 0.71 | MAOA (0.53) | ALDH1A1TSHRMAOAMAOBHTR1A | |
| SCHEMBL5980469 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAHTTNPC1 | |
| SCHEMBL5694454 | 0.69 | MAOA (0.47) | ALDH1A1TSHRMAOAMAOBHTR1A | |
| SCHEMBL15013797 | 0.69 | HTR1A (0.47) | ALDH1A1TSHRLMNAHTTMAOA | |
| SCHEMBL642607 | 0.69 | SLC6A4 (0.47) | ALDH1A1TSHRLMNAHTTMAOA | |
| SCHEMBL1835846 | 0.68 | ALDH1A1 (0.38) | ALDH1A1LMNAHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451191-A1 | THIOETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003050121-A1 | THIOETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |