SCHEMBL6676189

SCHEMBL6676189

CCNC(=N)Nc1cccc(CN)c1N(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CACNA1C Q13936 1/20 0.33
SCN5A Q14524 1/20 0.33
ALDH1A1 P00352 2/20 0.31
GAA P10253 2/20 0.31
MAPT P10636 1/20 0.31
AOC1 P19801 1/20 0.31
AOC3 Q16853 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6679054 0.99 CACNA1C (0.33) CACNA1CSCN5AALDH1A1GAAMAPT
SCHEMBL6676422 0.81 ALDH1A1 (0.42) CACNA1CSCN5AALDH1A1GAAMAPT
SCHEMBL6675316 0.81 PNMT (0.41) CACNA1CSCN5AALDH1A1GAAMAPT
SCHEMBL6676347 0.81 ALDH1A1 (0.39) CACNA1CSCN5AALDH1A1GAAMAPT
Hydrochloric Acid SCHEMBL6675363 0.80 ALDH1A1 (0.41) CACNA1CSCN5AALDH1A1GAAMAPT
Hydrochloric Acid SCHEMBL6674248 0.80 PNMT (0.40) CACNA1CSCN5AALDH1A1GAAMAPT
SCHEMBL6676762 0.78 GLS (0.35) CACNA1CSCN5AALDH1A1GAAMAPT
Hydrochloric Acid SCHEMBL6680715 0.77 GLS (0.35) CACNA1CSCN5AALDH1A1GAAMAPT
SCHEMBL6676191 0.75 CACNA1C (0.45) CACNA1CSCN5AALDH1A1GAAMAPT
Hydrochloric Acid SCHEMBL6679059 0.74 CACNA1C (0.44) CACNA1CSCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0798292-B1 ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) 2004-11-03 EP claimed