Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905022 | 0.78 | MAPT (0.36) | TDP1CA1CA2RAB9ANPC1 | |
| SCHEMBL548614 | 0.77 | CA1 (0.57) | TDP1CA1CA2RAB9ANPC1 | |
| SCHEMBL7906282 | 0.76 | MAPK1 (0.53) | TDP1RAB9ANPC1MAPTLMNA | |
| SCHEMBL8199784 | 0.73 | ALDH1A1 (0.40) | TDP1CA1CA2RAB9ANPC1 | |
| SCHEMBL13206086 | 0.71 | KIF11 (0.48) | TDP1CA1CA2RAB9AMAPT | |
| SCHEMBL6676922 | 0.71 | TDP1 (0.44) | TDP1CA1CA2RAB9AHDAC3 | |
| SCHEMBL12601247 | 0.71 | CYP17A1 (0.50) | TDP1CA1CA2RAB9ANPC1 | |
| SCHEMBL2594347 | 0.70 | RXRA (0.73) | HDAC3RXRAHDAC4HDAC1HDAC7 | |
| SCHEMBL31758293 | 0.70 | RXRA (0.73) | HDAC3RXRAHDAC4HDAC1HDAC7 | |
| SCHEMBL25832725 | 0.70 | CYP17A1 (0.40) | RAB9AHDAC2HDAC8HDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |