Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680339 | 0.89 | ADORA3 (0.66) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6683268 | 0.87 | MAPT (0.62) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6678084 | 0.86 | MAPT (0.72) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6677031 | 0.85 | LMNA (0.59) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6683414 | 0.85 | MAPT (0.62) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6682564 | 0.82 | MEN1 (0.59) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6684407 | 0.81 | KDM4E (0.70) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6676970 | 0.81 | MAPT (0.66) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6683017 | 0.79 | MAPT (0.68) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL6686801 | 0.79 | MEN1 (0.71) | MEN1KMT2AMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |