SCHEMBL667708

SCHEMBL667708

Cc1ccc(P(Cl)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 6/20 0.38
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
TSHR P16473 3/20 0.35
LMNA P02545 3/20 0.35
ALOX12 P18054 1/20 0.35
PKM P14618 2/20 0.35
HTT P42858 2/20 0.35
ATM Q13315 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
HPGD P15428 1/20 0.35
NLRP1 Q9C000 1/20 0.35
MEN1 O00255 1/20 0.35
NTSR1 P30989 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154839 0.89 ACHE (0.48) ACHETDP1ALDH1A1TSHRLMNA
SCHEMBL29274147 0.87 ACHE (0.62) ACHETDP1LMNAKMT2ASMN1; SMN2
SCHEMBL18868102 0.83 ACHE (0.65) ACHETDP1ALDH1A1CA2CA1
SCHEMBL2367541 0.81 ACHE (0.50) ACHETDP1ALDH1A1CA2CA1
SCHEMBL8016825 0.81 ACHE (0.50) ACHETDP1ALDH1A1CA2CA1
SCHEMBL10843494 0.75 ACHE (0.50) ACHETDP1ALDH1A1CA2CA1
SCHEMBL15661400 0.73 ACHE (0.57) ACHETDP1ALDH1A1CA2CA1
SCHEMBL34181 0.73 ACHE (0.57) ACHETDP1ALDH1A1CA2CA1
SCHEMBL8648548 0.73 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1
SCHEMBL19469302 0.73 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118530277-A Cationic photopolymerization type phosphate alicyclic epoxy monomer and preparation method and application thereof 北京化工大学 2024-08-23 CN claimed
CN-118063510-A Biphosphine ligand for synthesizing R-citronellal, preparation method and application thereof 浙江医药股份有限公司新昌制药厂 2024-05-24 CN claimed
EP-1598053-B1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres OREAL (FR) 2006-12-20 EP claimed
EP-1598053-A1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres L'OREAL (FR) 2005-11-23 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES BHATTACHARYA SHRABANTI (US) 2025-12-04 US disclosed
US-12398089-B2 Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) 2025-08-26 US disclosed
CN-119998255-A Catalytic carboxycarbonylation of olefins to form anhydrides 北卡罗来纳大学教堂山分校 2025-05-13 CN disclosed
CN-119930684-A C (C)2Symmetrical N-axis chiral bisindole diphosphine ligand and preparation method and application thereof 青岛大学 2025-05-06 CN disclosed
EP-4543841-A2 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES The University of North Carolina at Chapel Hill (US) 2025-04-30 EP disclosed
CN-119702082-A Supported catalyst and application thereof in synthesizing isononyl aldehyde through hydroformylation reaction 中国石油化工股份有限公司 2025-03-28 CN disclosed
CN-118530277-A Cationic photopolymerization type phosphate alicyclic epoxy monomer and preparation method and application thereof 北京化工大学 2024-08-23 CN disclosed
US-4496745-A Epoxycarbacyclin derivatives, their preparation and use SANKYO COMPANY, LIMITED (JP) 1985-01-29 US disclosed
EP-0110089-A2 Polymer-bound alkyl diarylphosphinite catalyst compositions and processes for making same and using same for selective conversion of acrylonitrile into 1,4-dicyano-1-butene ALLIED CORPORATION (US) 1984-06-13 EP disclosed
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed
US-4006185-A CHEMICAL INTERMEDIATES OLIN CORPORATION (US) 1977-02-01 US disclosed
US-3975447-A Preparation of aromatic phosphine oxides by reaction of diarylhalophosphine and benzylic halide E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-17 US disclosed
US-3965183-A FROM M-NITROACETANILIDE WITH HYDROGEN FLUORIDE OLIN CORPORATION (US) 1976-06-22 US disclosed
US-3960962-A AMMONIA, PALLADIUM-PHOSPHINATED POLYSTYRENE RESIN CATALYST ETHYL CORPORATION (US) 1976-06-01 US disclosed
US-3953510-A Method for the preparation of alkoxyanilines OLIN CORPORATION (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES CA4, CA12, CA14 ACHE 2398/4885TDP1 3585/4885ALDH1A1 688/4885
US-12398089-B2 Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand POF1B, ADH1C, OSBP ACHE 2444/4885TDP1 4211/4885ALDH1A1 447/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP ACHE 704/4885TDP1 3996/4885ALDH1A1 4512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.