Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL21591028 | 0.94 | DNM1 (0.42) | SPHK1ALDH1A1DNM1FDPSOPRM1 | |
| Hydrochloric Acid SCHEMBL17317377 | 0.78 | DNM1 (0.38) | ALDH1A1DNM1FDPSOPRM1CA2 | |
| Hydrochloric Acid SCHEMBL7865432 | 0.77 | DNM1 (0.41) | ALDH1A1DNM1FDPSOPRM1CA2 | |
| SCHEMBL18125197 | 0.74 | — | — | |
| SCHEMBL1657122 | 0.74 | — | — | |
| SCHEMBL16817228 | 0.74 | TSHR (0.42) | SPHK1ALDH1A1DNM1FDPSOPRM1 | |
| SCHEMBL18125180 | 0.74 | — | — | |
| SCHEMBL12209935 | 0.74 | — | — | |
| SCHEMBL18124779 | 0.74 | — | — | |
| SCHEMBL24855 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220186070-A1 | MULTI-FUNCTIONAL POLYURETHANE COATINGS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2022-06-16 | — | — | US | disclosed |
| EP-3921179-A1 | MULTI-FUNCTIONAL POLYURETHANE COATINGS | Hewlett-Packard Development Company, L.P. (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2021126141-A1 | PHOSPHONIUM-CONTAINING POLYURETHANE COMPOSITIONS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021076145-A1 | MULTI-FUNCTIONAL POLYURETHANE COATINGS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2021-04-22 | — | — | WO | disclosed |
| US-9278134-B2 | Dual functioning ionic liquids and salts thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2016-03-08 | — | — | US | disclosed |
| US-20120046244-A1 | DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2012-02-23 | — | — | US | disclosed |
| WO-2010078300-A1 | DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046244-A1 | DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF | SLC6A6, SLC10A2, CLK2 | BDKRB2 2702/4885SPHK1 3254/4885ALDH1A1 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.