Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26927426 | 0.87 | ALDH1A1 (0.44) | ALDH1A1HTTGAACLCN2POLB | |
| SCHEMBL11562589 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HTTGAACLCN2POLB | |
| SCHEMBL15015520 | 0.85 | HPGD (0.53) | ALDH1A1HTTGAAPTGS2LMNA | |
| SCHEMBL15015538 | 0.85 | CXCL8 (0.57) | CLCN2PTGS2MAPTKDM4E | |
| SCHEMBL3342778 | 0.84 | SCD (0.46) | ALDH1A1HTTPOLB | |
| Hydrochloric Acid SCHEMBL7406915 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HTTGAACLCN2POLB | |
| Hydrochloric Acid SCHEMBL9554099 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTGAACLCN2POLB | |
| SCHEMBL5692314 | 0.83 | PARP1 (0.51) | ALDH1A1GAAPTGS2MAPTMEN1 | |
| SCHEMBL7365033 | 0.83 | CYSLTR2 (0.48) | — | |
| SCHEMBL27551104 | 0.83 | PARP1 (0.43) | ALDH1A1HTTPTGS2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036832-C | Composition containing a penem or carbapenem artibiotic and the use of the same | SANKYO CO (JP) | 1997-12-31 | — | — | CN | claimed |
| CN-1095069-A | Novel process for the preparation and/or purification of clavulanic acid or pharmaceutically acceptable salts or esters thereof | SMITHKLINE BEECHAM PLC (GB) | 1994-11-16 | — | — | CN | claimed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | claimed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | claimed |
| CN-86107574-A | Compositions containing penem or carbapenem antibiotics and their use | — | 1987-05-20 | — | — | CN | claimed |
| CN-116888138-A | Radiopharmaceutical conjugate compositions and uses thereof | 瑞择生物公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-111148740-A | Compounds useful as autophagy modulators and methods of making and using the same | 微境生物医药科技(上海)有限公司 | 2020-05-12 | — | — | CN | disclosed |
| US-9073977-B2 | Biomimetic peptoid polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-07 | — | — | US | disclosed |
| US-20120046443-A1 | Novel biomimetic peptoid polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-23 | — | — | US | disclosed |
| CN-102134213-A | 5-(alpha-methoxylbenzyl)pyrrole compound as well as preparation method and application thereof | UNIV NANKAI | 2011-07-27 | — | — | CN | disclosed |
| WO-2010017412-A1 | NOVEL BIOMIMETIC PEPTOID POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20070135499-A1 | Hydrazide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | US | disclosed |
| CN-1095069-A | Novel process for the preparation and/or purification of clavulanic acid or pharmaceutically acceptable salts or esters thereof | SMITHKLINE BEECHAM PLC (GB) | 1994-11-16 | — | — | CN | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| CN-86107574-A | Compositions containing penem or carbapenem antibiotics and their use | — | 1987-05-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046443-A1 | Novel biomimetic peptoid polymers | NOD2, APP, SPPL2B | ALDH1A1 4856/4885HTT 2445/4885GAA 4275/4885 |
| US-20070135499-A1 | Hydrazide compounds | GRK4, GRK2, GRK1 | ALDH1A1 2861/4885HTT 641/4885GAA 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.