Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982109 | 0.98 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PLK1BIDMCL1 | |
| SCHEMBL3342778 | 0.95 | SCD (0.46) | CYSLTR2CYSLTR1PLK1BIDMCL1 | |
| SCHEMBL26927426 | 0.89 | ALDH1A1 (0.44) | SCD | |
| SCHEMBL667734 | 0.83 | ALDH1A1 (0.55) | — | |
| SCHEMBL11879454 | 0.81 | NAAA (0.49) | — | |
| SCHEMBL15861767 | 0.81 | POLB (0.56) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL25062002 | 0.80 | LIPG (0.50) | PLK1BIDMCL1BCL2L1BAK1 | |
| SCHEMBL2023026 | 0.79 | SLC16A3 (0.57) | CYSLTR2CYSLTR1PLK1BIDMCL1 | |
| SCHEMBL11458675 | 0.79 | SLC16A3 (0.57) | CYSLTR2CYSLTR1PLK1BIDMCL1 | |
| SCHEMBL2021245 | 0.79 | SLC16A3 (0.57) | CYSLTR2CYSLTR1PLK1BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712838-B1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD (JP) | 1998-11-04 | — | — | EP | claimed |
| US-5795891-A | RHEUMATOID ARTHRITIS, OSTEOPOROSIS, HYPERCALCEMIA | KANEBO LTD. (JP) | 1998-08-18 | — | — | US | claimed |
| EP-0712838-A1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD. (JP) | 1996-05-22 | — | — | EP | claimed |
| JP-7101925-A | — | — | None | — | — | JP | disclosed |
| EP-0712838-B1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0712838-B1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5795891-A | RHEUMATOID ARTHRITIS, OSTEOPOROSIS, HYPERCALCEMIA | KANEBO LTD. (JP) | 1998-08-18 | — | — | US | disclosed |
| US-5795891-A | RHEUMATOID ARTHRITIS, OSTEOPOROSIS, HYPERCALCEMIA | KANEBO LTD. (JP) | 1998-08-18 | — | — | US | disclosed |
| US-5795891-A | RHEUMATOID ARTHRITIS, OSTEOPOROSIS, HYPERCALCEMIA | KANEBO LTD. (JP) | 1998-08-18 | — | — | US | disclosed |
| CN-1038583-C | Acylphenylglycine derivative and preventive and remedy for diseases caused by increased collagenase activity containing said compound as active ingredient | KANEBO LTD (JP) | 1998-06-03 | — | — | CN | disclosed |
| CN-1038583-C | Acylphenylglycine derivative and preventive and remedy for diseases caused by increased collagenase activity containing said compound as active ingredient | KANEBO LTD (JP) | 1998-06-03 | — | — | CN | disclosed |
| CN-1133034-A | Acylphenylglycine derivative and preventive or remedy for diseases caused by increased collagenase activity containing the same as active ingredient | KANEBO LTD (JP) | 1996-10-09 | — | — | CN | disclosed |
| CN-1133034-A | Acylphenylglycine derivative and preventive or remedy for diseases caused by increased collagenase activity containing the same as active ingredient | KANEBO LTD (JP) | 1996-10-09 | — | — | CN | disclosed |
| EP-0712838-A1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0712838-A1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0712838-A4 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD (JP) | 1996-03-19 | — | — | EP | disclosed |
| JP-H07101925-A | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTING AND TREATING AGENT FOR DISEASES CAUSED BY EXCESSIVE COLLAGENASE ACTIVITY CONTAINING THE COMPOUND AS ACTIVE COMPONENT | KANEBO LTD | 1995-04-18 | — | — | JP | disclosed |
| WO-1995004715-A1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO, LTD. (JP) | 1995-02-16 | — | — | WO | disclosed |