Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683539 | 0.81 | ADORA3 (0.54) | KDM4EHTTRAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL6681047 | 0.79 | MEN1 (0.55) | KDM4EADORA3MAPTALDH1A1MEN1 | |
| SCHEMBL6681136 | 0.78 | MEN1 (0.57) | KDM4EADORA3MAPTCCNE1CDK2 | |
| SCHEMBL6677923 | 0.77 | CCNE1 (0.53) | KDM4EHTTRAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL6682326 | 0.77 | ALDH1A1 (0.57) | KDM4EHTTRAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL6682346 | 0.76 | KDM4E (0.49) | KDM4EHTTRAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL6678678 | 0.76 | ADORA3 (0.60) | KDM4EHTTSMN1; SMN2ADORA3MAPT | |
| SCHEMBL6683533 | 0.75 | KDM4E (0.50) | KDM4EHTTRAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL6684415 | 0.74 | SMN1; SMN2 (0.54) | KDM4EHTTRAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL6679128 | 0.74 | ALDH1A1 (0.53) | KDM4EHTTRAB9ASMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |