Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6677533 | 0.99 | SIGMAR1 (0.43) | SIGMAR1BACE1NOS1KDM4ENOS3 | |
| SCHEMBL6675448 | 0.84 | TAAR1 (0.46) | SIGMAR1BACE1NOS1KDM4ENOS3 | |
| Hydrochloric Acid SCHEMBL6675725 | 0.83 | TAAR1 (0.45) | SIGMAR1BACE1NOS1KDM4ENOS3 | |
| SCHEMBL6679341 | 0.82 | ATM (0.55) | KDM4EATMTAAR1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6675035 | 0.81 | ATM (0.54) | KDM4EATMTAAR1MAPTMAPK1 | |
| SCHEMBL6676406 | 0.77 | ADRA2A (0.54) | SIGMAR1NOS1NOS3NOS2TAAR1 | |
| Hydrochloric Acid SCHEMBL6689077 | 0.76 | ADRA2A (0.56) | SIGMAR1NOS1NOS3NOS2TAAR1 | |
| SCHEMBL6674697 | 0.75 | SIGMAR1 (0.57) | SIGMAR1NOS1 | |
| Hydrochloric Acid SCHEMBL7245672 | 0.74 | SIGMAR1 (0.56) | SIGMAR1NOS1 | |
| SCHEMBL6677583 | 0.74 | BACE1 (0.39) | BACE1KDM4ETAAR1ADRA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |