Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6675035 | 0.99 | ATM (0.54) | ATMKDM4ETAAR1TSHRMAPK1 | |
| SCHEMBL6677586 | 0.82 | SIGMAR1 (0.43) | ATMKDM4ETAAR1MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL6677533 | 0.81 | SIGMAR1 (0.43) | ATMKDM4ETAAR1MAPK1LMNA | |
| SCHEMBL6675448 | 0.81 | TAAR1 (0.46) | ATMKDM4ETAAR1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL6675725 | 0.80 | TAAR1 (0.45) | ATMKDM4ETAAR1MAPK1LMNA | |
| SCHEMBL6676245 | 0.76 | PTGIR (0.49) | TAAR1TSHRLMNACYP1A2NFKB1 | |
| SCHEMBL6679338 | 0.76 | TAAR1 (0.52) | ATMKDM4ETAAR1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL6679353 | 0.75 | PTGIR (0.48) | TAAR1TSHRLMNACYP1A2NFKB1 | |
| Hydrochloric Acid SCHEMBL6675033 | 0.75 | TAAR1 (0.54) | ATMKDM4ETAAR1TSHRMAPK1 | |
| SCHEMBL6676406 | 0.74 | ADRA2A (0.54) | TAAR1MAPK1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |