SCHEMBL6677708

SCHEMBL6677708

CC1=CCC([Si](C)(C)c2cccc3c2Cc2ccccc2-3)=C1C

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PGR P06401 1/20 0.35
HTR7 P34969 1/20 0.32
HTR2B P41595 1/20 0.32
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6675602 0.83 PNMT (0.39) PNMTNPC1RAB9APGRHTR7
SCHEMBL61027 0.81 PNMT (0.49) PNMTNPC1RAB9APGRHTR7
SCHEMBL29843943 0.81 PNMT (0.49) PNMTNPC1RAB9APGRHTR7
SCHEMBL6672321 0.78 PNMT (0.37) PNMTNPC1RAB9APGRHTR7
SCHEMBL7052932 0.77 PNMT (0.38) PNMTNPC1RAB9APGRHTR7
SCHEMBL6671922 0.74 PNMT (0.49) PNMTNPC1RAB9APGRHTR7
SCHEMBL5981385 0.74 PNMT (0.49) PNMTNPC1RAB9APGRHTR7
SCHEMBL6915753 0.73 PNMT (0.38) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL60587 0.72 PNMT (0.39) PNMTNPC1RAB9APGRHTR7
SCHEMBL6675582 0.72 PNMT (0.36) PNMTNPC1RAB9APGRHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
WO-2002004468-A1 METALLOCENE POLYMERIZATION CATALYST E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-01-17 WO disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 US disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed