SCHEMBL7052932

SCHEMBL7052932

CC1=CCC([Si](C)(C)c2cccc3c2Cc2ccccc2-3)=C1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
PGR P06401 1/20 0.33
HTR7 P34969 1/20 0.32
HTR2B P41595 1/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057186 0.84 PNMT (0.35) PNMTNPC1RAB9A
SCHEMBL61027 0.82 PNMT (0.49) PNMTNPC1RAB9APGRHTR7
SCHEMBL29843943 0.82 PNMT (0.49) PNMTNPC1RAB9APGRHTR7
SCHEMBL7937191 0.79 PNMT (0.39) PNMTNPC1RAB9APGRHTR7
SCHEMBL30901174 0.79 PNMT (0.39) PNMTNPC1RAB9APGRHTR7
SCHEMBL60587 0.79 PNMT (0.39) PNMTNPC1RAB9APGRHTR7
Hydrochloric Acid SCHEMBL29262831 0.77 PNMT (0.37) PNMTNPC1RAB9APGRHTR7
SCHEMBL6677708 0.77 PNMT (0.37) PNMTNPC1RAB9APGRHTR7
SCHEMBL6675602 0.76 PNMT (0.39) PNMTNPC1RAB9APGRHTR7
SCHEMBL5981385 0.75 PNMT (0.49) PNMTNPC1RAB9APGRHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed