Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17933519 | 0.77 | MAOA (0.55) | MEN1KMT2AMAOASIGMAR1CHRM2 | |
| SCHEMBL10814295 | 0.77 | HPGD (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11633335 | 0.75 | MAOA (0.50) | KDM4EALDH1A1HPGDHTTMAOA | |
| SCHEMBL9710515 | 0.74 | BRD4 (0.43) | BRD4CREBBPALDH1A1RYR2LMNA | |
| SCHEMBL8946181 | 0.67 | KDM1A (0.40) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6238887 | 0.67 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29836089 | 0.67 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29463396 | 0.67 | MAOA (0.40) | BRD4CREBBPALDH1A1HPGDMAOA | |
| SCHEMBL11217635 | 0.67 | MAOA (0.40) | BRD4CREBBPALDH1A1HPGDMAOA | |
| Hydrochloric Acid SCHEMBL11140336 | 0.67 | MAOA (0.69) | MAOAMAOBCHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040191855-A1 | Production of secondary metabolites | SYNEXA LIFE SCIENCES (PROPRIETARY) LIMITED (ZA) | 2004-09-30 | — | — | US | disclosed |
| EP-1425378-A2 | PRODUCTION OF SECONDARY METABOLITES | Synexa Life Sciences (Proprietary) Ltd (ZA) | 2004-06-09 | — | — | EP | disclosed |
| WO-2002094979-A2 | PRODUCTION OF SECONDARY METABOLITES | SYNEXA LIFE SCIENCES (PROPRIETARY) LTD (ZA) | 2002-11-28 | — | — | WO | disclosed |