Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678043 | 0.83 | LMNA (0.39) | RAB9ALMNAPKMALDH1A1HPGD | |
| SCHEMBL6679445 | 0.79 | KMT2A (0.40) | LMNAALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL6675265 | 0.67 | CYP19A1 (0.47) | ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL6679443 | 0.63 | TP53 (0.51) | LMNAALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL6677069 | 0.62 | CYP19A1 (0.50) | RAB9AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL28396699 | 0.62 | TP53 (0.50) | PKMALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL4322779 | 0.60 | RAB9A (0.58) | RAB9ALMNAALDH1A1HPGDAGTR1 | |
| SCHEMBL6675911 | 0.59 | RXFP1 (0.62) | RAB9AALDH1A1HTTMAPTNPSR1 | |
| SCHEMBL6678243 | 0.59 | RAB9A (0.58) | RAB9ALMNAPKMALDH1A1HTT | |
| SCHEMBL27686975 | 0.59 | TDP1 (0.46) | RAB9ALMNAPKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181341-B1 | LUMINESCENT 4-TRIFLUOROMETHYL-2-QUINOLONES WITH LONG-WAVE UV-ABSORPTION AND THE USE THEREOF | URAY GEORG (AT) | 2004-10-27 | — | — | EP | disclosed |