Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 6/20 | 0.53 |
| ▸ | RARB | P10826 | 4/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675571 | 1.00 | MMP2 (0.56) | MMP2HDAC1HDAC2MMP3RARB | |
| SCHEMBL6680243 | 0.89 | MMP2 (0.57) | MMP2HDAC1HDAC2MMP3RARB | |
| SCHEMBL6675503 | 0.89 | MMP2 (0.57) | MMP2HDAC1HDAC2MMP3RARB | |
| SCHEMBL3971811 | 0.88 | MMP2 (0.62) | MMP2HDAC1HDAC2MMP3RARB | |
| SCHEMBL6675501 | 0.85 | HRH2 (0.51) | MMP2HDAC1HDAC2MMP3RARB | |
| SCHEMBL6680399 | 0.85 | HRH2 (0.51) | MMP2HDAC1HDAC2MMP3RARB | |
| SCHEMBL6693875 | 0.84 | HDAC1 (0.41) | MMP2HDAC1HDAC2MMP3RARB | |
| Butane SCHEMBL3628845 | 0.84 | RARB (0.63) | MMP2HDAC1HDAC2MMP3RARB | |
| SCHEMBL8994937 | 0.80 | PLA2G4B (0.64) | ALDH1A1MAPTHPGDTP53TSHR | |
| SCHEMBL18079151 | 0.78 | HDAC1 (0.67) | MMP2HDAC1HDAC2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048499-A2 | COMBINED ROD-DISC CRYSTALLINE SYSTEMS WITH NEMATIC PROPERTIES | THE UNIVERSITY OF HULL (GB) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048499-A2 | COMBINED ROD-DISC CRYSTALLINE SYSTEMS WITH NEMATIC PROPERTIES | THE UNIVERSITY OF HULL (GB) | 2004-06-10 | — | — | WO | disclosed |