Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 4/20 | 0.56 |
| ▸ | MMP3 | P08254 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675503 | 1.00 | MMP2 (0.57) | MMP2HDAC1HDAC2RARBMMP3 | |
| SCHEMBL6675571 | 0.89 | MMP2 (0.56) | MMP2HDAC1HDAC2RARBMMP3 | |
| SCHEMBL6678136 | 0.89 | MMP2 (0.56) | MMP2HDAC1HDAC2RARBMMP3 | |
| SCHEMBL8994937 | 0.89 | PLA2G4B (0.64) | POLBCASP6ALDH1A1HPGDMAPT | |
| SCHEMBL3971811 | 0.87 | MMP2 (0.62) | MMP2HDAC1HDAC2RARBMMP3 | |
| SCHEMBL6676627 | 0.86 | HRH3 (0.51) | MMP2HDAC1HDAC2RARBMMP3 | |
| Butane SCHEMBL3628845 | 0.82 | RARB (0.63) | MMP2HDAC1HDAC2RARBMMP3 | |
| SCHEMBL3515601 | 0.80 | HRH3 (0.53) | MMP2HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL8994850 | 0.79 | PLA2G4B (0.53) | HDAC1HDAC2ALDH1A1HPGDMAPT | |
| SCHEMBL8995020 | 0.79 | PLA2G4B (0.53) | HDAC1HDAC2ALDH1A1MAPTPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048499-A2 | COMBINED ROD-DISC CRYSTALLINE SYSTEMS WITH NEMATIC PROPERTIES | THE UNIVERSITY OF HULL (GB) | 2004-06-10 | — | — | WO | claimed |