Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694819 | 0.88 | HDAC1 (0.42) | HDAC1HDAC2PTPN11MMP2MMP3 | |
| SCHEMBL6678136 | 0.84 | MMP2 (0.56) | HDAC1HDAC2MMP2RARBMMP3 | |
| SCHEMBL6675571 | 0.84 | MMP2 (0.56) | HDAC1HDAC2MMP2RARBMMP3 | |
| SCHEMBL6687717 | 0.80 | RARB (0.43) | HDAC1HDAC2RARBMMP3ALDH1A1 | |
| SCHEMBL6689371 | 0.80 | RARB (0.43) | HDAC1HDAC2RARBMMP3ALDH1A1 | |
| SCHEMBL6680243 | 0.74 | MMP2 (0.57) | HDAC1HDAC2PTPN11MMP2RARB | |
| SCHEMBL6675503 | 0.74 | MMP2 (0.57) | HDAC1HDAC2PTPN11MMP2RARB | |
| SCHEMBL3971811 | 0.74 | MMP2 (0.62) | HDAC1HDAC2MMP2RARBMMP3 | |
| SCHEMBL8994937 | 0.73 | PLA2G4B (0.64) | MAPTPLA2G4BPOLBALDH1A1HPGD | |
| SCHEMBL6675501 | 0.73 | HRH2 (0.51) | HDAC1HDAC2MMP2RARBMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048499-A2 | COMBINED ROD-DISC CRYSTALLINE SYSTEMS WITH NEMATIC PROPERTIES | THE UNIVERSITY OF HULL (GB) | 2004-06-10 | — | — | WO | claimed |