Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678527 | 0.82 | POLB (0.46) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL34511 | 0.77 | SELL (0.36) | ALDH1A1MAPTKDM4ESMN1; SMN2POLB | |
| SCHEMBL6678739 | 0.74 | DPP4 (0.35) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL1007016 | 0.73 | TSHR (0.48) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL6680960 | 0.71 | POLB (0.37) | CYP1A2CYP2A6ALDH1A1HSD17B10HPGD | |
| SCHEMBL1005445 | 0.67 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL919716 | 0.67 | CYP1A2 (0.38) | CYP1A2CYP2A6ALDH1A1HPGDMAPT | |
| SCHEMBL919718 | 0.67 | CYP1A2 (0.38) | CYP1A2CYP2A6ALDH1A1HPGDMAPT | |
| SCHEMBL6678521 | 0.66 | C5AR1 (0.40) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18527604 | 0.65 | CYP2D6 (0.35) | ALDH1A1HSD17B10HPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093475-B1 | CATALYST FOR THE POLYMERISATION OF OLEFINS | BOREALIS TECH OY (FI) | 2004-11-17 | — | — | EP | disclosed |
| US-6613851-B1 | Cyclic carbene- eta -ligand complexes for catalysis of olefin polymerization. | BOREALIS TECHNOLOGY OY (FI) | 2003-09-02 | — | — | US | disclosed |
| WO-2000078826-A1 | CATALYSTS | BOREALIS TECHNOLOGY OY (FI) | 2000-12-28 | — | — | WO | disclosed |