SCHEMBL34511

SCHEMBL34511

Cc1cc(C)c(N2[C]N(c3c(C)cc(C)cc3C)C=C2)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36
SELE P16581 1/20 0.36
RAPGEF4 Q8WZA2 3/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6680158 0.87 HRH3 (0.32) SELLSELPSELERAPGEF4ALDH1A1
SCHEMBL6678739 0.84 DPP4 (0.35) ALDH1A1KDM4EMAPTLMNA
SCHEMBL6677918 0.82
SCHEMBL6681602 0.82 KDM4E (0.35) ALDH1A1KDM4E
SCHEMBL8028616 0.80 GABRA1 (0.37) ALDH1A1POLBSMN1; SMN2
SCHEMBL6678441 0.77 CYP1A2 (0.42) ALDH1A1KDM4EMAPTPOLBSMN1; SMN2
SCHEMBL6679629 0.76 NR1I2 (0.32) POLBSMN1; SMN2LMNA
SCHEMBL6681680 0.75 ALDH1A1 (0.35) ALDH1A1KDM4EMAPTPOLBHTT
SCHEMBL16341301 0.75 ALDH1A1 (0.35) ALDH1A1KDM4EMAPTPOLBHTT
SCHEMBL6678521 0.74 C5AR1 (0.40) ALDH1A1MAPTPOLBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3016991-B1 LIQUID MOLDING COMPOSITIONS MATERIA INC (US) 2024-06-12 EP claimed
EP-4139281-B1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES UNIV HEIDELBERG (DE) 2024-05-08 EP claimed
EP-4359401-A1 PROCESS FOR PREPARING EGFR INHIBITORS Blueprint Medicines Corporation (US) 2024-05-01 EP claimed
WO-2024086429-A1 POLYMER FIBERS AND PARTICLES PRODUCED BY ELECTROSPINNING OR ELECTROSPRAYING SCALE HOLDINGS LLC (US) 2024-04-25 WO claimed
EP-3256505-B1 CYCLIC OLEFIN RESIN COMPOSITIONS COMPRISING FUNCTIONAL ELASTOMERS MATERIA INC (US) 2023-11-29 EP claimed
US-11821112-B1 Polymer fibers and particles produced by electrospinning or electrospraying SCALE HOLDINGS LLC (US) 2023-11-21 US claimed
EP-3805337-B1 INK COMPOSITIONS AND QUANTUM DOT POLYMER COMPOSITE PATTERN PREPARED FROM THE SAME SAMSUNG DISPLAY CO LTD (KR) 2023-08-09 EP claimed
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2023-05-18 US claimed
US-20230037920-A1 PAN-TACTIC CRYSTALLINE AND RECYCLABLE POLYTHIOESTERS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2023-02-09 US claimed
WO-2022271801-A1 PROCESS FOR PREPARING EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION (US) 2022-12-29 WO claimed
US-20060128935-A1 Manufacture of macrocyclic polyester oligomers E. I. DU PONT DE NEMOURS AND COMPANY 2006-06-15 US claimed
US-20060128912-A1 Transition metal carbene complexes containing a cationic substituent as catalysts of olefin metathesis reactions UTI LIMITED PARTNERSHIP (CA) 2006-06-15 US claimed
EP-1656924-A1 Metathesis-curable composition Kerr Corporation (US) 2006-05-17 EP claimed
US-7001590-B1 Metathesis-curable composition KERR CORPORATION (US) 2006-02-21 US claimed
WO-2005121158-A1 TRANSITION METAL CARBENE COMPLEXES CONTAINING A CATIONIC SUBSTITUENT AS CATALYSTS OF OLEFIN METATHESIS REACTIONS UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2005-12-22 WO claimed
WO-2005063834-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-07-14 WO claimed
US-20050137369-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2005-06-23 US claimed
US-20040254320-A1 Metathesis-curable composition with a reaction control agent KERR CORPORATION 2004-12-16 US claimed
US-6774274-B2 CATIONIC IRIDIUM CARBENE COMPLEXES; HYDROGENATION CATALYSTS CAPABLE OF HYDROGENATING SIMPLE OLEFINS AT ROOM TEMPERATURE UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION, INC. 2004-08-10 US claimed
US-20020173650-A1 Metal complexes for hydrogenation of unsaturated compounds UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION, INC. 2002-11-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128912-A1 Transition metal carbene complexes containing a cationic substituent as catalysts of olefin metathesis reactions SOD1, OPRM1, C1S SELL 1622/4885SELP 2785/4885SELE 1403/4885
US-20230037920-A1 PAN-TACTIC CRYSTALLINE AND RECYCLABLE POLYTHIOESTERS PARG, PLEKHA1, PANK1 SELL 4848/4885SELP 4677/4885SELE 3801/4885
US-20020173650-A1 Metal complexes for hydrogenation of unsaturated compounds INTS6, PRDX6, PRDX2 SELL 2720/4885SELP 3241/4885SELE 3741/4885
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES TST, CBS, CTH SELL 1522/4885SELP 1074/4885SELE 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.