Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677918 | 0.79 | — | — | |
| SCHEMBL8144157 | 0.77 | CYP2D6 (0.50) | CYP2D6MEN1LMNAKMT2ANPSR1 | |
| SCHEMBL8144347 | 0.77 | CYP2D6 (0.50) | CYP2D6MEN1LMNAKMT2ANPSR1 | |
| SCHEMBL852612 | 0.77 | CYP2D6 (0.50) | CYP2D6MEN1LMNAKMT2ANPSR1 | |
| SCHEMBL6678739 | 0.74 | DPP4 (0.35) | LMNAKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL34511 | 0.73 | SELL (0.36) | LMNANPSR1KDM4EALDH1A1MAPT | |
| SCHEMBL19030908 | 0.70 | CYP2D6 (0.41) | CYP2D6MEN1LMNAKMT2ANPSR1 | |
| SCHEMBL6678521 | 0.69 | C5AR1 (0.40) | MEN1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL6678441 | 0.65 | CYP1A2 (0.42) | CYP2D6MEN1LMNAKMT2AKDM4E | |
| SCHEMBL8028616 | 0.65 | GABRA1 (0.37) | CYP2D6MEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10744494-B2 | Immobilized metal alkylidene catalysts and use thereof in olefin metathesis | XIMO AG (CH) | 2020-08-18 | — | — | US | claimed |
| EP-3394074-B1 | IMMOBILIZED METAL ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | XIMO AG (CH) | 2019-10-09 | — | — | EP | claimed |
| US-20190001315-A1 | IMMOBILIZED METAL ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | KiMo AG (CH) | 2019-01-03 | — | — | US | claimed |
| EP-3394074-A1 | IMMOBILIZED METAL ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | XiMo AG (CH) | 2018-10-31 | — | — | EP | claimed |
| WO-2017109199-A1 | IMMOBILIZED METAL ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | XIMO AG (CH) | 2017-06-29 | — | — | WO | claimed |
| US-10744494-B2 | Immobilized metal alkylidene catalysts and use thereof in olefin metathesis | XIMO AG (CH) | 2020-08-18 | — | — | US | disclosed |
| EP-3394074-B1 | IMMOBILIZED METAL ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | XIMO AG (CH) | 2019-10-09 | — | — | EP | disclosed |
| US-20190001315-A1 | IMMOBILIZED METAL ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | KiMo AG (CH) | 2019-01-03 | — | — | US | disclosed |
| EP-3394074-A1 | IMMOBILIZED METAL ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | XiMo AG (CH) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017109199-A1 | IMMOBILIZED METAL ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | XIMO AG (CH) | 2017-06-29 | — | — | WO | disclosed |
| US-20170050994-A1 | N-Heterocyclic Carbene Complexes Of Metal Imido Alkylidenes And Metal OXO Alkylidenes, And The Use Of Same | Universität Stuttgart (DE) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10744494-B2 | Immobilized metal alkylidene catalysts and use thereof in olefin metathesis | AOC2, AOC3, AOX1 | CYP2D6 677/4885MEN1 1934/4885LMNA 4104/4885 |
| US-20170050994-A1 | N-Heterocyclic Carbene Complexes Of Metal Imido Alkylidenes And Metal OXO Alkylidenes, And The Use Of Same | NR2C2, NR2E3, NR0B2 | CYP2D6 1244/4885MEN1 1485/4885LMNA 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.